The completion of cognition and tasks requires the orchestration of spatiotemporal processes distributed in the brain. Structural connectivity provides the fundamental substrate of this communication. Functional connectivity and effective connective respectively elucidate the correlation and directional information flow subserving the neuronal network. We use magnetic resonance imaging (MRI),  magnetoencephalography (MEG), and electroencephalogrqphy (EEG) to study the structural, functional, and effective connectivity at the system level.

Selected publication

Brain hemodynamic activity during viewing and re-viewing of comedy movies explained by experienced humor“, Iiro P. Jääskeläinen, Juha Pajula, Jussi Tohka, Hsin-Ju Lee, Wen-Jui Kuo, Fa-Hsuan Lin, Scientific Reports, (6), Article number: 27741, doi:10.1038/srep27741

Increasing fMRI sampling rate improves Granger causality estimates“,Fa-Hsuan Lin, Jyrki Ahveninen, Tommi Raij, Thomas Witzel, Ying-Hua Chu, Iiro P. Jääskeläinen, Kevin Wen-Kai Tsai, Wen-Jui Kuo, John W. Belliveau, PLoS ONE, 9(6): e100319. doi:10.1371/journal.pone.0100319

Effective cerebral connectivity during silent speech reading revealed by functional magnetic resonance imaging“, Ying-Hua Chu, Fa-Hsuan Lin, Yu-Jen Chou, Kevin W.-K. Tsai, Wen-Jui Kuo, Iiro P. Jääskeläinen, PLoS ONE 8(11): e80265. doi:10.1371/journal.pone.0080265

Functional and Effective Connectivity of Visuomotor Control Systems Demonstrated Using Generalized Partial Least Squares and Structural Equation Modeling“, Fa-Hsuan Lin, John A. Agnew, John W. Belliveau, Thomas A. Zeffiro, Human Brain Mapping, (2009), Vol. 30, pp. 2232-2251

Dynamic Granger causality modeling with application to interictal spike propagation“, Fa-Hsuan Lin, Keiko Hara, Vic Solo, Mark Vangel, John Belliveau, Steven Stufflebeam, Matti Hämäläinen, Human Brain Mapping, (2009), Vol. 30, pp. 1877-1896

Spectral spatiotemporal imaging of cortical oscillations and interactions in the human brain“, Fa-Hsuan Lin, Thomas Witzel, Matti S. Hämäläinen, Anders M. Dale, John W. Belliveau, Steven M. Stufflebeam, NeuroImage (2004) Vol. 23, pp. 582-595